Statistical literacy is the ability to master statistical concepts, applications, calculations and interpretations. This research is an experiment that aimed to investigate the effectiveness of a learning module for statistical literacy. The presented research focused on discussing and describing the effectiveness of a learning module for statistical literacy. The selected sample involved the public health students of STIKES BBM Majene; 20 students in class A as the sample for try-out I and 25 students in class B as the sample of try-out II by using One Group Pre-test and Post-test Design. The data was collected with the use of an achievement test of statistical literacy, and data was analyzed with the use of Descriptive Statistical Analysis, N-Gain Calculations, and Paired Sample t Test. Research results revealed that the average N-Gain in try-out I was 0.59, and the average N-Gain in try-out II was 0.61, each of which was in the moderate category. Moreover, in try-out I, the mean score of the post-test was 22.15, which was higher than and significantly different from the mean score of the pre-test, which was 10.66. Meanwhile, in try-out II, the mean score of the post-test was 22.68, which was higher than and significantly different from the mean score of the pre-test, which was 10.96. Therefore, the learning module for statistical literacy was effective.