Kaliningrad is a unique Russian region due to its history and geopolitical location. During the Cold War era it was considered an important Soviet military outpost in the confrontation with the NATO. After collapse of the Soviet Union region found itself in a completely new situation as a Russian enclave in Europe. The new geopolitical situations led to numerous problems. After the Poland and Lithuania joining the UE a new set of problems looms ahead. The regional and central governments tried to found a development strategy for Kaliningrad enclave. Now Kaliningrad is open for international cooperation and has one of the most liberal economic and border regime in Russian Federation. Russian government establish on Kaliningrad region Special Economic Zone to attract foreign investment. However Kaliningrad is still a problem form both partners: Russian Federation and UE.