This article suggests one of the possible ways of integrating teaching methods from the integration methods developed by the authors, namely: the integration based on the dominant teaching method. The article aims to substantiate the author’s methods of integrative teaching based on the dominant method and present the results of the approbation of these methods in higher schools. The project was implemented within the course “Medical Biophysics”. An integration algorithm as a dominant teaching method is proposed. The project contained several specific techniques. In the first specific method, the situational method is chosen as the dominant one. For the second one, the method of trials and coincidences is dominant. For diagnostics as a complex topic in medicine, physics, chemistry and other sciences, the problem method as dominant is dominant. In all methods, several other methods are gradually integrated into the dominant method, depending on the content and nature of the educational material. The practical significance of the project is to create algorithms for integrating teaching methods and the possibility of their transformation into other educational topics. The approbation shows an increase in the indicators of saving time and flexibility of knowledge.